Hereditary Hemorrhagic Telangiectasia Presenting as High Output Cardiac Failure during Pregnancy
نویسندگان
چکیده
High-output cardiac failure secondary to hepatic involvement is a rare complication of hereditary hemorrhagic telangiectasia (HHT). Here we report a 43-year-old woman who presented at 29 weeks gestation of her second pregnancy with complications of right-sided heart failure and preterm labor. After delivery via cesarean section, the patient was found to have intrahepatic arteriovenous malformations through non-invasive imaging. Subsequently, a family history of vascular malformations and epistaxis was elucidated and a diagnosis of HHT was made. This case is presented, along with a review of the literature and discussion of hepatic involvement in HHT with particular focus on the pregnant patient.
منابع مشابه
Hereditary Hemorrhagic Telangiectasia With Liver Vascular Malformation Presenting With High-Output Heart Failure
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant genetic disease manifested by formation of telangiectasias and visceral vascular malformations of organ systems, including the skin, lungs, gastrointestinal tract, brain, and liver. Hepatic involvement may lead to portal hypertension, high-output cardiac failure, and biliary strictures.1 Diagnosis requires patients to have 3 o...
متن کاملAnesthetic implications for the parturient with hereditary hemorrhagic telangiectasia.
PURPOSE To review the effects of hereditary hemorrhagic telangiectasia (HHT) in the parturient and the anesthetic management of such patients during pregnancy and delivery. SOURCE A literature search (1966-2008) was performed using Medline and EMBASE databases. Bibliographies of retrieved articles were searched for additional sources. PRINCIPAL FINDINGS Hereditary hemorrhagic telangiectasia...
متن کاملTwo Cases of High Output Heart Failure Caused by Hereditary Hemorrhagic Telangiectasia
High-output cardiac failure is a rare complication of hereditary hemorrhagic telangiectasia (HHT) usually caused by shunting of blood through atriovenous malformations (AVMs) in the liver. We describe two cases of high output heart failure due to large hepatic AVMs. Clinical suspicion of HHT based on detailed history taking and physical examination is essential for early detection and proper ma...
متن کاملHereditary hemorrhagic telangiectasia and pregnancy: potential adverse events and pregnancy outcomes
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant condition with a prevalence of ~1 in 5,000 individuals. The pathophysiology of this condition centers on the lack of capillary beds between arterioles and venules, leading to direct contact between these vessels. This results in telangiectases on characteristic locations such as the face, fingers, mouth, and nasal mucosa. Visc...
متن کاملOutcomes of pregnancy in women with hereditary hemorrhagic telangiectasia.
OBJECTIVE To describe pregnancy outcomes in women with hereditary hemorrhagic telangiectasia (HHT). METHODS This was a retrospective descriptive study of women with HHT (18-55 years of age) from the Toronto HHT Database using a telephone questionnaire regarding pregnancy, delivery, and neonatal outcomes. RESULTS A total of 244 pregnancies were reported in 87 women with HHT. Miscarriages occ...
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ورودعنوان ژورنال:
دوره 2009 شماره
صفحات -
تاریخ انتشار 2009